What does the harm that pregnant albuminuria is tall have

Update Date: 2022-05-27 Source: Network

summary

My sister has been pregnant for several months. Now her stomach is getting bigger. A few days ago, she went to the hospital for routine examination and found that the urine protein is too high. It is said that it has certain harm. Let me talk about the harm of high urine protein in pregnancy.

What does the harm that pregnant albuminuria is tall have

First: the high risk of maternal urine protein, maternal urine protein found positive consideration is due to pregnancy induced hypertension syndrome (formerly known as pregnancy poisoning), this disease can cause damage to renal function, it is recommended to actively adjust blood pressure, avoid the use of drugs that damage renal function, bed rest, the vast majority of protein can disappear after delivery.

Second, large amount of urine protein is one of the main risk factors for the progression of chronic kidney disease to end-stage renal failure, so it should be an important target for the treatment of chronic kidney disease. Mesangial toxicity of urinary protein: in the model of proteinuria nephropathy, there are low density lipoprotein (LDL) and very low density lipoprotein (VLDL) apolipoprotein B and apolipoprotein A deposits in the glomerulus, which can eventually lead to glomerulosclerosis.

Third: the toxic effect of urinary protein on proximal convoluted tubular cells: when proteinuria occurs, the amount of protein entering the renal tubular epithelial cells increases, which increases the activity of lysosome, suggesting that protein causes lysosome to overflow into the cytoplasm of tubular cells, and subsequent cell damage can stimulate inflammation and scar formation.

matters needing attention

Generally speaking, there are two causes of high urine protein in pregnant women, one is high pregnancy, and the second is nephritis. The former generally does not need to worry too much, just pay more attention to it, while the latter is more harmful. At this time, we need to consult a doctor how to treat it.