Late symptoms of retroperitoneal tumor?

summary

The most common symptom of retroperitoneal tumor is pain, including abdominal pain, low back pain, leg pain, etc. Abdominal pain or low back pain may occur in 44% - 75% of patients. The nature of pain can be dull pain, severe pain or colic. Most of the pain sites are tumor sites, sometimes difficult to locate. Abdominal and low back pain usually do not cause loss of mobility. Late symptoms of retroperitoneal tumor? Let's talk about it.

Late symptoms of retroperitoneal tumor?

Gastrointestinal symptoms such as nausea, vomiting, changes in bowel habits and constipation are more common in these patients. Abdominal distension may occur in 4% - 35% of patients, and intestinal obstruction may occur in some patients. Anorexia, weight loss, fatigue and weakness are often the manifestations of retroperitoneal malignant tumors. 40% - 50% of retroperitoneal malignant tumors have such symptoms in the late stage, and only 3% in the early stage.

Sometimes patients may present with urogenital symptoms, which are closely related to retroperitoneal tumors located in the pelvis or adjacent kidneys and ureters. Urinary tract symptoms may include hematuria, frequency of urination, urgency of urination, pain of urination, dysuria, and a few have oliguria or anuria. These symptoms are caused by urinary tract compression with or without direct renal and ureteral involvement. Sometimes patients with retroperitoneal tumors may have azotemia caused by bilateral ureteral obstruction.

If the retroperitoneal tumor originated from the pelvic extraperitoneal or spread to the pelvic, it can compress or invade the lumbar plexus or sacral plexus nerve roots, resulting in low back pain radiating to one or both lower limbs. Sometimes tumor infiltrates intervertebral foramen, leading to compression of notochord, which can cause incontinence and paralysis of lower limbs. Edema of perineum and lower limbs and varicose veins are other secondary manifestations of tumor spreading to the basin. Obstruction of pelvic venous and lymphatic return sometimes leads to unilateral edema, sometimes even bilateral lower limb edema. When the tumor causes inferior vena cava obstruction, if it is acute obstruction, it can cause obvious edema of both lower limbs. If it is chronic obstruction, it can produce rich collateral circulation.

matters needing attention

Other clinical manifestations of retroperitoneal tumors include abdominal or flank tension, abdominal distention, splenomegaly, large lymph nodes, pallor, cough, shortness of breath, venous thrombosis, intra-abdominal hemorrhage, jaundice, cachexia, etc.