What causes nephrotic syndrome in children

summary

My children have been in poor health since childhood, with low immunity, and often get sick. In the past two years, their thighs have been swollen severely, they are weak all over, and they eat less. When doing physical examination, they found that they suffered from chronic nephrotic syndrome. Many of my friends also questioned the cause of nephrotic syndrome. As far as I know, let's analyze it!

What causes nephrotic syndrome in children

First of all, there is more than one cause of nephrotic syndrome. Chronic nephritis is an immune disease due to infection, which causes damage to the internal environment and immune balance disorder. Its etiology and pathology is not a single kidney disease, but a series of diseases of the whole body.

Secondly, the disease of nephrotic syndrome has a certain relationship with the immune system of human body. Due to the disorder of human immune balance, the kidney is diffuse on both sides, and a few of them are focal segmental mesangial proliferation, membrane proliferation, membranous, minimal lesions, focal sclerosis. In the late stage, most glomeruli are fibrotic or glassy, the glomerular cortex becomes thinner, the glomerular capillaries atrophy, and finally the majority of nephrons disappear The volume of the kidney was reduced, and even became shrunken.

Finally, the cause of most nephrotic syndrome is unknown. Chronic glomerulonephritis is a group of chronic glomerular diseases with multiple causes. However, the etiology of chronic glomerulonephritis in most patients is unknown and has no clear relationship with Streptococcus infection. According to statistics, only 15% - 20% of the patients have changed from acute glomerulonephritis to acute glomerulonephritis. However, because the subclinical type of acute glomerulonephritis is not easy to be diagnosed, the actual percentage may be higher.

matters needing attention

When we find kidney disease, we often lose confidence in our own body, but we need to insist on treatment. When we find that the renal function is slowly declining, in addition to drug treatment, doctors usually recommend patients to reduce protein intake, so as to reduce the burden of the kidney and delay the time of becoming end-stage renal disease. In addition to limiting protein, doctors also choose to limit sodium according to the different conditions Or phosphorus or water diet.