Does propranolol treat portal hypertension?

summary

Propranolol propranolol "propranolol" is used to treat arrhythmias caused by many reasons, such as atrial and ventricular premature beats (better effect), sinus and supraventricular tachycardia, atrial fibrillation, etc., but ventricular tachycardia should be used with caution. Antimony poisoning caused by arrhythmia, when other drugs ineffective, you can try this product. In addition, it can also be used for angina pectoris, hypertension, pheochromocytoma (preoperative preparation), etc. In the treatment of angina pectoris, it is often combined with nitrates. It can improve the curative effect and counteract each other's adverse reactions. It has a certain curative effect on hypertension, and is not easy to cause postural hypotension.

Does propranolol treat portal hypertension?

Propranolol is non selective β 1 and β 2. Adrenoceptor blocker can slow down heart rate, weaken myocardial contractility, reduce cardiac output, and increase peripheral resistance reflex at the initial stage α The renal blood flow and glomerular filtration rate, coronary artery and other visceral organs blood flow decreased. Propranolol can affect the function of adrenergic neurons, the sensitivity of central nervous system blood pressure regulation baroreceptor, and competitively antagonize the effects of isoprenaline and noradrenaline.

Plasma renin activity factor β It can also cause vasoconstriction and bronchospasm. It has the effect of enhancing insulin and reducing blood sugar, and also has effect on the combination of prostaglandin E2. It can inhibit the secretion of renin and has no orthostatic hypotension. The mechanism of treating tremor may be related to β It may also be a central role.

It is used to treat arrhythmia caused by many reasons, such as atrial and ventricular premature beat (better effect), sinus and supraventricular tachycardia, atrial fibrillation, etc., but ventricular tachycardia should be used with caution. Antimony poisoning caused by arrhythmia, when other drugs ineffective, you can try this product. In addition, it can also be used for angina pectoris, hypertension, pheochromocytoma (preoperative preparation), etc. In the treatment of angina pectoris, it is often combined with nitrates. It can improve the curative effect and counteract each other's adverse reactions. It has a certain curative effect on hypertension, and is not easy to cause postural hypotension.

matters needing attention

(1) Allergic history（ 2) Congestive heart failure（ 3) First degree atrioventricular block（ 4) Diabetes mellitus（ 5) Emphysema or non allergic bronchitis（ 6) Liver dysfunction（ 7) Hypothyroidism（ 8) Raynaud's syndrome or other peripheral vascular diseases（ 9) Renal function decreased（ 10) Anesthesia or surgery patients（ 11) Pregnant and lactating women.