What is acute agranulocytosis?

summary

Acute agranulocytosis is more serious than neutropenia. It refers to sudden onset and severe agranulocytosis with absolute value less than 0.5 × 109 / L, a syndrome characterized by fever and infection. Schultz first reported 6 cases in 1922, and later studies found that most patients had this syndrome. What is acute agranulocytosis? Next, I'd like to share my views with you.

What is acute agranulocytosis?

Acute onset, chills or chills, high fever, headache, weakness, often accompanied by oral mucosa, gums, tongue, soft palate, and pharyngeal necrotic ulcer, covered with gray or green black pseudomembrane.

Rectum, anus, vagina, uterus and other mucosa also have the same ulcer. Submandibular and cervical lymph nodes are often swollen, and a few cases have jaundice, liver and spleen enlargement. The progress of the disease can cause lung or other parts of the infection, until sepsis.

Like other agranulocytosis, the inflammatory infiltration of the infection focus is not obvious, and pus rarely forms. About 10% of the patients developed rashes. Hemopoietic growth factor (HGF) was immediately administered with either feggistine (rhG CSF) or saxagliptine (rhGM CSF) for 5 days μ 5 g / (kg · d) × 109 / L or more.

matters needing attention

1. Can not eat food rich in vitamins 2, can not eat food without iron 3, eat less, easy to digest, can not overeat 4, according to the disease symptomatic diet