Neonatal symptoms of hemophilia?

summary

Hemophilia I believe we are not unfamiliar, is due to the lack of blood coagulation cells caused. This disease is mainly caused by heredity, so we must do eugenics, preventive measures in advance to avoid the occurrence of hemophilia. So what are the symptoms of hemophilia in infants? Now let's learn about it together, and hope to bring you more help.

Neonatal symptoms of hemophilia?

(1) Hemophilia A A and B have similar clinical manifestations. The earlier the bleeding symptoms appear, the more serious the disease is. Hemophilia A a usually occurs when infants begin to learn to climb and walk. There are few cases within 9 months after birth. Occasionally, the bleeding does not stop when the umbilical cord is broken. Mild cases can only be found in adults, Hemophilia B is rare in severe cases, but most of the mild cases occur within 2 years old, and a few are later than 5-6 years old.

(2) Joint hemorrhage: it is one of the special manifestations of children with hemophilia A. about 75% of hemophilia A A patients often occur after exercise and trauma. Ankle joint involvement is common in infants, and knee joint involvement is common in children. There is mild discomfort before bleeding, and then local joint redness, swelling, heat, pain and limited activity. If the amount of bleeding is small, timely treatment and joint hematoma can be absorbed, However, repeated bleeding of joints often leads to articular cartilage destruction, narrowing of articular cavity, atrophy of muscles around joints, formation of chronic hemophilic arthritis, even joint deformity and loss of function.

(3) Hemophilia muscle hemorrhage and hematoma: the lower limbs, forearms, buttocks are more common, deep hematoma has corresponding parts of pain, compression symptoms, such as the amount of bleeding, can cause shock, anemia, jaundice and fever, subcutaneous, gingival, oral and nasal mucosa are easy to be injured, so it is the bleeding prone parts, but skin and mucous membrane hemorrhage is not the characteristics of the disease, skin ecchymosis, ecchymosis are rare, If the bleeding occurs in the pharynx and larynx, it is easy to cause asphyxia, gastrointestinal bleeding and hematuria. Hematuria in children is easily misdiagnosed as "nephritis". If no corresponding measures are taken in children's tooth removal or surgical operation, such as tooth extraction and tonsillectomy, it will cause persistent bleeding or bleeding. Intracranial hemorrhage is rare and can be spontaneous, but it is usually caused by trauma, which is often life-threatening, The possibility of intracranial hemorrhage or subdural hemorrhage should be paid attention to in hemophilia children with severe headache. Hemophilia C homozygous children have the tendency of hemorrhage, and the hemorrhage is mild, which mostly occurs after surgery or trauma, and spontaneous hemorrhage is rare; The degree of bleeding has no significant relationship with the concentration of factor XI. Children often lack coagulation factors such as factor V and factor VII. Heterozygous children have no bleeding symptoms.

matters needing attention

For hemophilia, a hereditary blood disease, early treatment will achieve better therapeutic effect, reduce the pain of patients and make them return to normal life. After treatment, nursing measures should be strengthened in daily life to prevent bleeding.