What causes vitiligo

summary

My vitiligo has been suffering from 3 years, has been treated, some time ago found a new method, the results used after the spread of vitiligo, and quickly found a large hospital, is currently actively cooperating with the doctor treatment, how much has improved, about what is the cause of vitiligo? Do you understand? Let's talk about what causes vitiligo.

What causes vitiligo

First: vitiligo is a common acquired localized or generalized skin depigmentation disease. However, the mechanism is still unclear. It can occur in all parts of the body, common in finger back, wrist, forearm, face, neck and around genitalia. The decrease of copper or ceruloplasmin levels in the blood and skin of patients with vitiligo leads to the decrease of tyrosinase activity, which affects the metabolism of melanin.

Second: female vulva can also occur, young women in the majority. Vitiligo can appear in twins and families, indicating that heredity plays an important role in the pathogenesis of vitiligo. Studies have shown that vitiligo has incomplete penetrance and multiple pathogenic loci. Vitiligo can be combined with autoimmune diseases, such as thyroid disease, diabetes, chronic adrenal insufficiency, pernicious anemia, rheumatoid arthritis, malignant melanoma and so on.

Third: mental factors are closely related to the onset of vitiligo. Most patients have mental trauma, excessive tension, depression or depression at the onset or skin lesion development stage. The degeneration of nerve endings in leukoplakia also supports the neurochemical theory. Antibodies and T lymphocytes can be produced in patients with vitiligo, indicating that the immune response may lead to the destruction of melanocytes.

matters needing attention

Warm tips: Patients with vitiligo should not be exposed to the sun, but the appropriate sun is good for treatment. When the sun slants on the ground, it is better to choose around noon. The sun exposure time can be longer. At the end of spring and summer, the sun is directly on the ground, in the morning and evening. If you choose noon, you can irradiate through the glass room. The irradiation time can be shorter and the number of times can be more. In this way, the skin damage caused by intense sunlight can be reduced, which is conducive to the therapeutic effect of long wave ultraviolet.