What are the causes of liver cancer

summary

In the past two days, I found a lot of liver cancer patients in the ward. Seeing that everyone has different clinical symptoms, and the body is getting weaker and weaker, I can't help feeling sad. Many people don't know much about the cause of liver cancer. Next, I'll talk about the cause of liver cancer.

What are the causes of liver cancer

First: viral hepatitis. About one third of patients with primary liver cancer have a history of chronic hepatitis. According to the national census, the incidence rate of hepatitis is also high in the high incidence area of primary liver cancer. Epidemiological investigation showed that the positive rate of HBsAg in high incidence area was higher than that in low incidence area, and the positive rate of serum HBsAg in patients with liver cancer was significantly higher than that in healthy people. In recent years, lichen red staining and other methods have been used to show the presence of HBsAg in hepatoma cells. In addition, it has also been confirmed that HBV (hepatitis B virus) can be integrated into the DNA of host liver cells. A human hepatoma cell line capable of producing HBsAg has been established.

Second: liver cirrhosis, the incidence of primary liver cancer with liver cirrhosis is very high, according to domestic statistics is about 50-90%, and liver cirrhosis with liver cancer is 30-50%. Liver cancer with cirrhosis is mostly large nodular. This type of cirrhosis is mostly caused by viral hepatitis. Hepatocellular carcinogenesis may occur in the process of hepatocyte regeneration, that is, carcinogenesis through hepatocyte Destruction Proliferation dysplasia. Liver cancer often occurs on the basis of alcoholic cirrhosis in Europe and the United States. It is generally believed that biliary cirrhosis and congestive cirrhosis have nothing to do with the occurrence of primary liver cancer.

Third: Aflatoxin has a strong carcinogenic effect on rats, ducks, guinea pigs and other animals. Aflatoxin B1 is the strongest carcinogen in animal liver cancer. Epidemiological investigation found that in some areas with high incidence of liver cancer, the contamination of grain, oil, food (such as corn, wheat, soybean, peanut, etc.) by aflatoxin B1 is often serious, but it is rare in low incidence areas. All of these suggest that aflatoxin may be the cause of liver cancer in some areas, but there is no direct evidence of liver cancer in human.

matters needing attention

Many patients suffer from hepatitis or cirrhosis for some reasons. If the disease continues to deteriorate without treatment, it is easy to cause liver cancer. For patients with liver cancer, the treatment methods are radiotherapy, chemotherapy and surgery, these methods are very good, can increase the survival of patients.