Digoxin poisoning symptoms?
summary
Digoxin is a kind of cardiotonic glycoside, which is white crystal or crystalline powder; Odorless; It tastes bitter. During the treatment, the effect on the heart is positive inotropic effect, which slows down the heart rate and inhibits the cardiac conduction. It is suitable for low output congestive heart failure, atrial fibrillation, atrial flutter and paroxysmal supraventricular tachycardia. Among digoxin drugs, digoxin excreted rapidly and accumulated less. The oral absorption was incomplete and irregular. The plasma concentration of digoxin was 2.73-3.9 nmol / L in human and the lethal dose was 10 mg in adults. Digoxin poisoning symptoms? Let's talk about it
Digoxin poisoning symptoms?
1. The early symptoms of poisoning include gastrointestinal reactions, such as nausea, vomiting, diarrhea, anorexia, and systemic symptoms, such as headache, dizziness, fatigue, insomnia, etc.
2. Cardiotoxicity, can appear all kinds of arrhythmia, heart rate slow down, ventricular premature contraction, multiple sources and multiple premature contractions, showing two or three rhythms, causing supraventricular tachycardia, atrioventricular block, atrioventricular node inhibition, sinus arrest, severe cases can occur ventricular tachycardia, ventricular fibrillation, even cardiac arrest, sudden death.
3. Visual changes, including yellow vision, green vision and blurred vision. Nervous system performance, early headache, insomnia, can appear disorientation, delirium, mental disorders, seizures, etc.
matters needing attention
1. It should not be compatible with acids and bases. 2. Caution: hypokalemia; Incomplete atrioventricular block; Hypercalcemia; Hypothyroidism; Ischemic heart disease; miocardial infarction; Myocarditis; Renal function damage.