What symptom does albuminuria have?

summary

High proteinuria refers to the abnormal amount of proteinuria found in the urine, which is a bad sign that the kidney of diabetic patients may be damaged. Proteinuria early diabetic nephropathy has no clinical proteinuria, only radioimmunoassay can detect microalbuminuria. The only early manifestation of clinical diabetic nephropathy is proteinuria, which gradually develops from intermittent to persistent. If the course of diabetes is more than 5 years, the renal function, urine protein quality, 24-hour urine protein quantity, blood pressure and fundus examination should be checked frequently. So, what symptom does albuminuria have? Let's talk about it.

What symptom does albuminuria have?

The symptoms of diabetic nephropathy include proteinuria, edema, anemia, hypertension and renal failure. Proteinuria is an important indicator for the diagnosis of nephropathy. Proteinuria accounts for 4.9% ~ 10% of diabetic patients. The course of disease was shorter than 10 years, proteinuria accounted for 1% ~ 3%; The course of disease was longer than 20 years, proteinuria accounted for 12.8%; The course of disease was longer than 35 years, proteinuria accounted for 62%.

The symptom of early diabetic nephropathy is no edema, with the increase of urinary protein, plasma protein decreased, edema. Edema mainly occurs in the face, lower limbs and ankles, waist and back, a few patients with rapid progress of the disease may have hypoproteinemia and systemic edema. After proteinuria, glomerular filtration rate decreased, renal function began to decline, urea nitrogen increased, azotemia appeared, and renal failure could develop. It has been reported that about 20% of the patients developed renal failure within 6 years, 50% within 10 years and 75% within 15 years after proteinuria. The average survival time was about 15 years.

The symptoms of diabetic nephropathy may also have mild to moderate anemia, which is caused by the disorder of erythropoiesis caused by azotemia. Long term proteinuria can be hypertension, and can aggravate the disease, make it worse.

matters needing attention

If possible, urine microprotein should be measured and analyzed β 2-microglobulin assay. Early detection of diabetic nephropathy. If the microalbuminuria increases, it should be measured 3 times in 3-6 months. To determine whether it is persistent microalbuminuria. If the increase of microalbumin can be determined and other factors causing the increase can be excluded, such as urinary tract infection, exercise induced hypertension, we should be highly vigilant and pay attention to control blood glucose to make it as close to normal as possible. If the blood pressure is more than 18.7/12kpa, we should actively reduce the blood pressure to keep it in the normal range. At the same time, low salt and low protein diet should be emphasized, with high quality protein as the best.