How is urethral stricture to return a responsibility?

summary

My husband is always uncomfortable recently. Inflammatory urethral stricture is caused by specific or non-specific urethral infection. Gonorrhea urethral stricture is the most common type of specific infection, followed by tuberculosis; In nonspecific infection, urethral stricture of the external orifice and penis caused by repeated inflammation of prepuce and glans is more common. Recurrent gonococcal urethritis makes the urethral wall form a wide range of scar tissue, which can be segmental or long segment urethral stricture. The scar goes deep into the whole layer of the urethra and even the tissue around the urethra, resulting in urethral lumen occlusion. How can the urethral stricture be caused.

How is urethral stricture to return a responsibility?

Patients must know that in normal male urethra, the disease is covered by pseudostratified columnar epithelial cells located on the basement membrane. Under the basement membrane, there is a connective tissue layer of urethral cavernous body and smooth muscle fibers rich in vascular sinuses. The main cell components of this connective tissue are fibroblasts, and the extracellular matrix is mainly collagen fibers. Fibroblasts are activated after trauma or inflammation, Proliferation.

Patients must pay attention to the fact that the speed of synthesizing collagen fiber I is faster than that of collagen fiber III, so that the ratio of collagen III to collagen I is lower than that of normal urethral cavernous body, the stretch and compliance are reduced, and the urethral lumen becomes narrow. After the stenosis is formed, the tension at the proximal end of the stricture is higher than that at the distal end during urination, The ability of fibroblasts to synthesize collagen fibers is different under different tension.

Patients must understand that when urinating, the proximal urethra expands due to high pressure, and residual urine appears in the expanded urethra. Due to poor drainage and poor blood supply of urethral mucosa, infection is easy to occur. When urinating under high pressure, urethral mucosa rupture can occur, causing urinary extravasation, and then periurethral inflammation, periurethral abscess, and periurethral infection will further aggravate the stenosis.

matters needing attention

Patients must go to large hospitals for regular treatment, do a comprehensive examination, early detection and early treatment, patients must actively cooperate with the doctor's treatment, do not have a negative heart, usually pay more attention to personal hygiene, I wish you health.