What disease does pantoprazole sodium treat?
summary
Gastric, duodenal ulcer patients should eat less acid, too sweet, too spicy food, do not drink strong tea and coffee. Pantoprazole is the final link of gastric acid secretion in which parietal cells are activated to form activity and inhibit H +, K + - ATPase in acidic environment. What disease does pantoprazole treat mainly?
What disease does pantoprazole sodium treat?
Pantoprazole enteric coated tablets, like other proton pump inhibitors and H2 receptor antagonists, decreased gastric acid secretion and increased gastrin level after pantoprazole treatment. This increase in gastrin levels is reversible. Because pantoprazole binds to the distal end of the enzyme at the cellular receptor level, pantoprazole can affect gastric acid secretion independently or under the stimulation of other substances (acetylcholine, histamine, gastrin). Oral and intravenous pantoprazole can achieve the same effect.
Indications of pantoprazole enteric coated tablets: duodenal ulcer, gastric ulcer, moderate and severe reflux esophagitis. The combination of pantoprazole enteric coated tablets and the following drugs can eradicate Helicobacter pylori infection: Clarithromycin and amoxicillin, or clarithromycin and metronidazole, or amoxicillin and metronidazole (see the medication method for details) to reduce the recurrence of duodenal ulcer and gastric ulcer caused by the microbial infection.
Pantoprazole may reduce the absorption of drugs (such as ketoconazole) whose bioavailability depends on the pH value in the stomach. Please note that this also applies to drugs that are applied shortly before oral administration of pantoprazole. The active ingredient of pantoprazole is metabolized by cytochrome P450 enzyme system in the liver, so it is impossible for other drugs metabolized by this enzyme system to interact with it. However, many drugs such as carbamazepine, caffeine, Anding, diclofenac, digoxin, ethanol, glibenclamide, metoprolol, nifedipine, dexamethasone, dexamethasone, dexamethasone, dexamethasone, dexamethasone, dexamethasone, dexamethasone, dexamethasone, dexamethasone, dexamethasone, dexamethasone, dexamethasone However, there was no significant interaction between pantoprazole and coumarin, phenytoin, theophylline, warfarin and oral contraceptives. Pantoprazole did not interact with other basic antacids.
matters needing attention
Due to the side effects, in order to reduce the occurrence of these unnecessary discomfort, we need to pay attention to the strict control of the dosage, and we also need to pay attention to the comprehensive understanding of the heart, liver and other organs before medication. Once the original disease, in addition to reducing the dosage, we also need to limit the time used, It can prevent further damage of liver, heart and other parts after drug application. After medication, you need to observe closely. If you feel uncomfortable, you need to inform the doctor in time to avoid serious consequences.
