What is the cause of myasthenia

summary

I think we all have a certain understanding of myasthenia. This disease is also one of the most distressing diseases. We are all very clear about myasthenia, but we are not very clear about the causes of myasthenia. What are the causes of myasthenia? Now let's get to know it together!

What is the cause of myasthenia

First, myasthenia gravis is an autoimmune disease of striated muscle postsynaptic membrane. Neuromuscular junction combines with sarcolemma receptor by receiving excitatory neurotransmitter transmission such as acetylcholine and nicotine, resulting in ion channel opening, inward flow, sarcolemma depolarization, end plate potential, muscle filament sliding, and muscle contraction.

Second: genetic and viral infections are well known that myasthenia is an abnormal autoimmune response, but the cause of the initiation of autoimmunity has not been fully understood.

Third: the transmission of nerve and muscle junction is impaired. The antibody of choline receptor (AChR) naturally destroys the AChR on the postsynaptic membrane at the neuromuscular junction, so that the synaptic transmission is impaired, which can not cause the full contraction of skeletal muscle and lead to myasthenia gravis.

matters needing attention

Myasthenia is a very serious disease, if not treated in time, the consequences are very terrible. If we know the cause of myasthenia, we can effectively prevent it, and at the same time, we can effectively treat it according to the cause, so it is necessary to understand the cause of myasthenia.