Symptoms of HIV infection

summary

AIDS, also known as acquired immune deficiency syndrome, is a fatal chronic infectious disease caused by human immunodeficiency virus (HIV). The virus mainly invades and destroys helper T lymphocytes, causing severe cellular immune deficiency in human body, and then complicated with various serious opportunistic infections and tumors, leading to death. The incubation period of AIDS varies greatly The incubation period of AIDS is related to the immune state of the body, the dose of infection, the route of infection and the nutritional health of the whole body. Today we will learn about HIV infection - Analysis and performance.

Symptoms of HIV infection

First, the asymptomatic period can be extended from the acute stage after the symptoms of infection disappear, or the acute infection period can be directly entered. Clinically, there are no symptoms, and antibodies to hivrna, core protein and envelope protein can be found in the blood, which is infectious and actually the incubation period of AIDS. It is the virus that destroys CD4, T lymphocytes and other immune cells until the immune function deteriorates. If the viral load in blood is less than 1000 copies / ml, it indicates that the duration of this period is longer, and the patients with longer incubation period may be one of the better prognostic factors.

Second: AIDS related syndrome: patients already have the most basic characteristics of AIDS, namely cellular immune deficiency, but the symptoms are mild. The main manifestations are fever, night sweats, diarrhea, fatigue lasting for more than one month, weight loss of more than 10%; accompanied by headache, personality change, memory loss, apathy, and even neuropsychiatric symptoms of dementia; in addition, there are two or more lymph nodes enlargement in other parts of the body except inguinal lymph nodes. The diameter of the enlarged lymph nodes is more than 1 cm, and there is no pain in the local area. Generally, the swelling is more than 3 months, some of them are more than 1 year, and some of them are enlarged again.

Third, opportunistic infections and tumors. With the decrease of CD4 T lymphocytes and the increase of viral load, opportunistic infection became common. For example, protozoa such as Toxoplasma gondii and Cryptosporidium, viruses such as cytomegalovirus, herpes simplex virus, human papillomavirus, possibly combined with HCV and HBV, and bacteria such as Streptococcus, Streptococcus pneumoniae and Haemophilus influenzae are 10-20 times higher than ordinary people. Mycobacterium tuberculosis is the most common bacterial infection of HIV / AIDS and the first cause of death of HIV infection. There are also many fungal infections. Now it is found that Pneumocystis Yersinia is the one that infects people. However, in the past, it was thought that Pneumocystis carinii caused pneumonia

matters needing attention

AIDS is mainly in the body's immune system suffered serious damage, the emergence of a variety of opportunistic infections and secondary tumors, various organs and systems of the body may be damaged, so this performance is diverse, once patients with AIDS, we must actively treat to avoid serious impact.