How to prevent senile leukoencephalopathy?

summary

Leukoencephalopathy refers to leukoencephalopathy, which is a structural change of the brain. It will affect our normal life. It is mainly characterized by myelin damage of central nerve cells. The lesions involve the white matter tracts which play a special role in the high-level brain function. Its clinical manifestations range from inattention, forgetfulness and personality change to dementia, coma and even death. Now I'd like to introduce how to prevent leukoencephalopathy in the elderly?.

How to prevent senile leukoencephalopathy?

First, most patients with leukoencephalopathy are reversible, but a few are irreversible. Therefore, if appropriate preventive measures are taken, the symptoms of patients can be significantly improved. The treatment of leukoencephalopathy has some limitations, and there is no unified treatment plan at present. Therefore, prevention is very important.

Second, most of the patients were treated with glucocorticoids and anticoagulant therapy. There were 6 breast cancer patients with leukoencephalopathy caused by 5-fluorouracil chemotherapy. Among them, 5 patients were treated with glucocorticoid at the early stage of symptoms, and the clinical symptoms were improved. In addition, the occurrence of leukoencephalopathy was not associated with age, gender, pathology and breast cancer stage. Therefore, the researchers believe that once 5-fluorouracil induces leukoaraiosis, high-dose glucocorticoid should be used.

Third: the leukoaraiosis caused by methotrexate toxicity can be treated with calcium formyltetrahydrofolate. For the development of specific treatment of leukoencephalopathy, it is necessary to determine which anti-tumor drugs can cause leukoencephalopathy damage, and the location of leukoencephalopathy damage caused by chemotherapy, such as myelin sheath, axon, oligodendrocyte, astrocyte and vascular system of leukoencephalopathy. Future nonspecific therapies include inducing intact oligodendrocytes to repair demyelinated axons and form new myelin sheath; Or embryonic stem cell transplantation.

matters needing attention

1. Eat high protein food; 2. Eat high vitamin food; 3. Eat high calorie food.