Can inflammatory myopathy be cured?
summary
Can inflammatory myopathy be cured? Idiopathic inflammatory myopathy is a group of inflammatory rhabdomyopathy with unclear etiology. The onset of the disease is mostly insidious, and the disease develops to the peak in weeks or months. It is characterized by progressive weakness of muscles around the hip, shoulder, neck and pharynx.
Can inflammatory myopathy be cured?
The therapeutic principles are as follows: 1; 2. Symptomatic and supportive treatment, prevention and treatment of various infections; 3. Plasma exchange therapy; 4. High dose gamma globulin treatment; 5. Whole body radiotherapy for stubborn and severe cases. Corticosteroids were used. Prednisone 40-60mg / D, once daily. Hydrocortisone 200-300 mg / D or dexamethasone 10-20 mg / D was added to 10% glucose in critically ill patients. When the patient's condition is stable, the dosage should be adjusted to achieve the best curative effect, and the least side effect is the maintenance dosage, sometimes as long as 2-3 years. During the course of treatment, ACTH should be used intermittently.
Principles of medication: 1. Adrenocortical hormone (dexamethasone, prednisone (prednisone)), hydrocortisone, methylprednisolone (methylprednisolone)) are effective for most of polymyositis, which is the first choice for the treatment of this disease. It is generally advocated that high-dose shock therapy and medium dose consolidation therapy should be used in the early stage, and the time should not be less than 3 months, and the maintenance time of low-dose should not be less than 2 years. 2. Immunosuppressants (cyclophosphamide, azathioprine or methotrexate) should be used or added to patients with ulcers, hypertension and diabetes, who can not use adrenocortical hormone, and whose myasthenia and myalgia have not improved after 3 months of regular hormone treatment, especially for patients with malignant tumor. 3. High dose of gamma globulin and plasma exchange therapy have therapeutic effect on the disease, but it needs higher medical costs. 4. Long term large-scale use of hormones, immunosuppressants, etc., we should pay attention to the side effects of drugs, strengthen symptomatic and supportive treatment, and use sufficient effective antibiotics as soon as possible for patients with infection.
Patients with dysphagia should be given nasal feeding to ensure adequate nutrition. Tracheotomy and assisted breathing should be performed in time in patients with respiratory tract obstruction or respiratory muscle paralysis. Qianglining has hormone like effect without side effect, so it can be used. 40 mg v.d. once a day. If the hormone is ineffective in large dose and short course, the drug should be stopped and immunosuppressant can be used instead. Azathioprine is 100-200mg daily. Pay attention to the side effects. Norone propionate 25mg intramuscular injection twice a week is effective in relieving pain and symptoms.
matters needing attention
Remove the possible incentives, such as wind cold, damp heat and other adverse factors on the human body. Strengthen physical exercise, life rules, pay attention to the combination of work and rest, enhance physique, reduce risk factors such as smoking, drinking, improve their immunity. Strengthen nutrition and prevent infection. Eat foods rich in vitamin C, such as fresh vegetables and fruits.
