What is lupus nephritis

summary

I believe that many people are familiar with nephritis, but few people know something about lupus nephritis. Next, I would like to share with you what is lupus nephritis

What is lupus nephritis

First of all, SLE is more common in women, the ratio of male to female is 1 ∶ 13, but male and female patients have the same high rate of renal involvement, the average age of onset is 27-29 years old, 85% of patients are under 55 years old. Systemic lupus erythematosus (SLE) is a systemic disease, which can involve multiple systems and organs. About 70% of SLE patients had clinical manifestations of renal damage. Combined with immunofluorescence and electron microscopy, 100% of SLE patients had renal involvement. Often because of infection, cold, sunlight, alcohol, stress, overwork or mental stress and other factors lead to disease attack or aggravation, but also because of improper use of hormones, rapid reduction or sudden withdrawal of drugs and cause recurrence. Every recurrence will aggravate the damage of the involved organs, and even lead to functional failure.

Secondly, the etiology of SLE and lupus nephritis (LN) has not been fully defined. It is thought that it is caused by many factors, such as heredity, virus infection, immune abnormality, sunlight or ultraviolet radiation, some drugs and estrogen. The renal disease caused by ln is typical autoimmune complex nephritis.

Finally, the current treatment of lupus nephritis more common drug is adrenocortical hormone, this drug for the treatment of lupus nephritis effect is more obvious.

matters needing attention

Lupus nephritis disease in daily life must pay attention to their work and rest habits, do not appear to stay up late, eat more light food, usually do not appear the habit of holding urine.