Causes of polycystic kidney disease

summary

My grandfather always has low back pain during this period of time. We took him to the hospital for examination. The doctor said it was polycystic kidney disease, and suggested taking medicine for treatment. Conservative therapy is good for my grandfather. But through treatment, the disease has been controlled to a certain extent. For the cause of polycystic kidney disease, let me tell you.

Causes of polycystic kidney disease

First: gene mutation (non genetic). For polycystic kidney disease, most of them are inherited through parents' genes, which are divided into autosomal dominant inheritance and autosomal recessive inheritance. However, some patients with polycystic kidney disease are neither inherited by parents nor belong to congenital dysplastic polycystic kidney disease, but gene mutation during embryogenesis.

Second: all kinds of infections. Infection can cause abnormal changes in the internal environment of the organism, thus creating environmental conditions conducive to the genetic changes of cysts, enhancing the activity of internal factors of cysts, thus promoting the birth and growth of cysts; and any infection in any part of the body will enter the kidney through blood, thus affecting cysts. If cysts are infected, it will not only aggravate the clinical symptoms, but also promote the growth of cysts It can accelerate the growth of cyst and aggravate the damage of renal function.

Third: congenital dysplastic renal cyst. Congenital dysplasia can produce a variety of diseases. For cystic nephropathy, it can mainly cause medullary sponge kidney, dysplastic polycystic kidney disease, etc. the gene of congenital dysplasia is not abnormal, so it is different from gene inheritance or gene mutation.

matters needing attention

If polycystic kidney disease is not treated as early as possible, it may enter the stage of uremia. Polycystic kidney uremia is due to the increase of cyst compression of renal parenchyma, renal ischemic renal damage and renal function, conventional western medicine at this time, only long-term dialysis and detoxification treatment, and finally developed to the point of renal replacement.