How to do with type V hyperlipoproteinemia?
summary
Hyperlipoproteinemia type V is also known as fat and sugar induced hyperlipidemia, hyperchylomicronemia and hyperbilirubinemia β- Lipoproteinemia, endogenous and exogenous hyperlipidemia, and calorie induced hyperlipidemia. Hyperlipoproteinemia caused by the increase of chylomicrons and VLDLs is a combination of type I and type IV hyperlipoproteinemia. The incidence rate is low, mostly in adults. It is considered to be a subtype of type IV and is often associated with obesity and / or alcoholism. When the supply of exogenous triglyceride is reduced, it changes to type IV. How to do with type V hyperlipoproteinemia?
How to do with type V hyperlipoproteinemia?
The etiology of hyperlipoproteinemia is the combination of type I and type IV of hyperlipoproteinemia. Endogenous triglyceride synthesis in liver was increased, chylomicronemia was also found, and the level of lipoprotein protease was decreased in some patients.
Clinical manifestations, skin manifestations for eruptive xanthoma, arteriosclerosis incidence is not clear, may have hepatosplenomegaly, abdominal colic, hyperuricemia and hyperglycemia. Triglyceride more than 1000 mg / dl can cause acute pancreatitis.
Diagnosis, serum turbidity or milk like, triglycerides continue to increase, higher than 1000 mg / dl, total cholesterol levels always rise, but LDL cholesterol is usually lower. VLDLs and chylomicrons increased. Glucose tolerance test and uric acid level determination should be done. According to the clinical manifestations, the characteristics of skin lesions and the characteristics of serum examination, the diagnosis can be made.
matters needing attention
Treatment, secondary factors of hypertriglyceridemia, such as diabetes or hypothyroidism, should be screened and treated if they exist. The decisive factor is to reduce the weight to the normal range through strict control of calorie intake and alcohol abuse. Drugs: the main application of beta drugs and nicotinic acid derivatives. Patients who do not receive treatment may have coronary heart disease and recurrent pancreatitis.
