Causes of vitiligo

summary

My big cousin suffers from vitiligo, which has been a disease for some time. There are several white plaques on her arm. When these plaques are serious, there will be peeling symptoms. Vitiligo has brought a very big impact on my big cousin's life. Recently, I went to the hospital for treatment, and the doctor also told us some reasons for suffering from vitiligo.

Causes of vitiligo

Reason 1: mental factors are closely related to the onset of vitiligo. Most patients have mental trauma, excessive tension, depression or depression at the onset or skin lesion development stage. The degeneration of nerve endings in leukoplakia also supports the neurochemical theory.

Reason 2: vitiligo can appear in twins and families, indicating that heredity plays an important role in the pathogenesis of vitiligo. Studies have shown that vitiligo has incomplete penetrance and multiple pathogenic loci.

Reason 3: vitiligo can be combined with autoimmune diseases, such as thyroid disease, diabetes, chronic adrenal insufficiency, pernicious anemia, rheumatoid arthritis, malignant melanoma, etc. The specific antibodies of various organs can also be detected in serum, such as anti thyroid antibody, anti gastric parietal cell antibody, anti adrenal antibody, anti parathyroid antibody, anti smooth muscle antibody, anti melanocyte antibody, etc.

matters needing attention

For patients with vitiligo this disease, to achieve early detection and early treatment, vitiligo patients can produce antibodies and T lymphocytes, indicating that the immune response may lead to the destruction of melanocytes. The precursor of toxic melanin synthesized by cells themselves and some chemical substances that cause skin discoloration may also selectively destroy melanocytes.