What is the cause of menopausal breast cancer?

summary

Breast cancer is a serious threat to women of all ages. The incidence rate of breast cancer is significantly increased in women with severe obesity and central fat accumulation after menopause. Estrogen can increase the incidence of breast cancer after perimenopausal period. High level prolactin also increases the incidence of breast cancer. What is the cause of menopausal breast cancer? Next, I'd like to share my views with you.

What is the cause of menopausal breast cancer?

The underlying cause of breast cancer has not been fully understood, but some factors may be an important factor in inducing breast cancer. The incidence rate of postmenopausal breast cancer is significantly increased in adult women with severe obesity and central fat accumulation. Obesity may affect breast cells through estrogen bioavailability and lipid metabolism.

Ovarian endocrine plays an important role in the pathogenesis of breast cancer. Estrogen and progesterone are important endocrine hormones closely related to the onset of breast cancer. The risk of breast cancer in women whose menarche age is earlier than 13 years old and who have menstruation for more than 40 years is more than twice that of ordinary women. The incidence rate of breast cancer gradually increases with the delay of the age of primipara.

The risk of breast cancer in patients with breast fibrocystic disease can be increased by 2-4 times. Genetic factors play an important role in the pathogenesis of breast cancer. With the development of molecular biology technology and the development of human genome project, it has been confirmed that there are at least two breast cancer susceptibility genes, BRCA1 and BRCA2, located on chromosome 17 and 13, respectively, BRCA1 or BRCA2 genetic mutation carriers have up to 90% risk of breast cancer in their lifetime, and about 5% - 10% of breast cancer is associated with genetic susceptibility.

matters needing attention

Should be light, eat more fruits and vegetables, reasonable diet, pay attention to adequate nutrition, please follow the doctor's advice. Early detection of early breast cancer is the core and key of "three early". In recent years, due to the popularity of health knowledge, a small number of patients with early breast cancer have been found in the outpatient department