What is athetosis?
summary
What is athetosis? Hand foot bradycardia is also known as finger stroke movement, or variable spasm. It is characterized by the increase and decrease of muscle tension in the distal part of the limb, and the slow torsion like peristalsis like earthworm crawling. Similar to dystonia, it is not an independent disease unit, but a relatively slow, aimless, continuous involuntary movement syndrome of fingers, toes, tongue or other parts of the body.
What is athetosis?
The common causes of HFA are: ① hereditary or familial: most of them are autosomal recessive inheritance, which is rare; ② Cerebrovascular accident; ③ Intracranial infection; ④ Drugs; ⑤ Cerebral palsy: cerebral palsy caused by various reasons can appear hand foot bradykinesia; ⑥ High cervical spinal cord lesions.
Hereditary or familial is mostly autosomal recessive inheritance, which is rare. In Japan, a familial gene of dystonic chorea is located in 2q31-36, and can be further located between d2s164 and d2s377. This region encodes PDC gene. At present, an X-linked hereditary disease, located in Xp11, has been found, It was also accompanied by mental retardation and abnormal behavior; Other hereditary neurological diseases, such as leukodystrophy, spinocerebellar ataxia, hepatolenticular degeneration and familial hypoproteinemia, may also be accompanied by hand foot hyperactivity disorder.
The occlusion of Heubner's recurrent artery in infants with cerebrovascular accident can lead to hand foot movement in contralateral limbs. Acute thalamic and globus pallidus infarction in adults can lead to hand foot movement. Autopsy shows a lacunar state in the posterior limb of internal capsule. Dementia, myoclonus and bilateral finger movement were found in patients with intracranial lentivirus infection. MRI showed atrophy of bilateral caudate nucleus and putamen and high signal intensity on T2WI; Herpes simplex virus, Mycoplasma pneumoniae, Toxoplasma gondii and AIDS intracranial infection can also cause hand foot hyperactivity disorder and so on.
matters needing attention
It is more important to prevent hand foot hyperactivity disorder with genetic background. Preventive measures include avoiding consanguineous marriage, carrying out genetic counseling, carrier gene testing, prenatal diagnosis and selective abortion to prevent the birth of children. Early diagnosis, early treatment and strengthening clinical nursing are of great significance to improve the quality of life of patients with hand foot hyperactivity disorder.
