What disease is corneal chroma ring?

summary

Corneal chroma ring is one of the clinical manifestations of biliary cirrhosis. Biliary cirrhosis is caused by long-term retention of intrahepatic bile or obstruction of extrahepatic bile duct. The former is called primary biliary cirrhosis, and the latter is called secondary biliary sclerosis. What disease is corneal chroma ring? Let's talk about it

What disease is corneal chroma ring?

The liver is swollen, light green, smooth or granular, and hard. The process of tissue injury is as follows: infiltration of lymphocytes and plasma cells, deposition of IgM and immune complex, which is the cause of granuloma. Bile reflux, bile duct injury and inflammation around bile duct,

In the proliferative stage of bile duct, due to the progressive destruction of chronic inflammation, the bile duct is replaced by fibrous tissue. It is difficult to find interlobular bile duct in most portal areas, but there is atypical hyperplasia of bile duct. Granuloma can still be seen in this stage. The capillary bile ducts around the hepatic lobules were extremely dilated, containing concentrated bile embolus. The capillary bile ducts were ruptured, forming bile paste. The surrounding hepatocytes were swollen, and the cytoplasm was loose, showing a transparent network, that is, hairy degeneration.

In the scarring stage, the content of collagen in the portal area increased, while the inflammatory cells and bile ducts decreased. Occasionally, lymphoid follicles were accompanied by hair centers. Fibrosis was most common in the medium-sized portal area. Granuloma was not common. Fibrous septa extended from the portal area to another portal area, or to the hepatic lobules, So that the boundary plate is blurred.

matters needing attention

Liver cirrhosis often died of complications. Upper gastrointestinal bleeding is the most common complication of liver cirrhosis, and hepatic encephalopathy is the most common cause of death. Therefore, the principles of treatment and prevention of liver cirrhosis are: reasonable diet, balanced nutrition, improvement of liver function, anti fibrosis treatment and active prevention of complications.