What examination does gout diagnose do?

summary

In recent decades, the typical gout is becoming increasingly rare, it will affect our normal life, replaced by a variety of atypical gout performance, make the clinical manifestations of gout more complex, coupled with the medical level of different places, it is very easy to cause gout misdiagnosis or missed diagnosis. Next, I'd like to introduce to you what kind of examination to make gout diagnosis?.

What examination does gout diagnose do?

First, the determination of serum urate and the increase of serum uric acid level are the important clinical biochemical characteristics of gout patients. Generally speaking, the level of serum uric acid in patients with gout who have not received treatment is higher, but it can be seen that the level of serum uric acid in some patients with acute attack of gout is in the normal range. Therefore, the low level of serum uric acid should not be used as the basis for excluding gout.

Second: Determination of uric acid salt. Through the determination of uric acid salt in urine, we can understand the excretion of uric acid, which is conducive to the clinical judgment that the disease is caused by excessive production of uric acid and excretion disorder. It has certain guiding significance for the selection of appropriate treatment drugs. This examination has a family history of gout, younger age, significantly increased serum uric acid level, lower blood uric acid level Patients with kidney stones are particularly important.

Thirdly, the activity of PRPP synthase, prppat, HPRT and xanthine oxidase in red blood cells of patients can be tested if conditions permit, which will help to determine the site of enzyme deficiency.

matters needing attention

During the attack of gout, the number of leukocytes in peripheral blood increased, ESR increased and C-reactive protein increased. When acute uric acid nephropathy affects glomerular filtration function, blood urea nitrogen and creatinine increase.