Clinical symptoms of type 2 diabetic nephropathy?

Update Date: 2021-09-23 Source: Network

summary

Diabetic nephropathy is a common complication of diabetes, is one of the manifestations of diabetic systemic microangiopathy, clinical characteristics of proteinuria, progressive renal damage, hypertension, edema, late severe renal failure, is one of the main causes of death in patients with diabetes. Clinical symptoms of type 2 diabetic nephropathy? Let's talk about it.

Clinical symptoms of type 2 diabetic nephropathy?

1. Albuminuria began because of the glomerular filtration pressure increased and the charge change on the filtration membrane, only microalbumin appeared in the urine, which was selective albuminuria, and there was no increase of globulin. This state could last for many years. With the increase of glomerular basement membrane filtration pore, macromolecular substances can pass through and non selective clinical proteinuria occurs. With the further development of the disease, urinary protein gradually becomes persistent severe proteinuria. If urinary protein exceeds 3 g / day, it is a sign of poor prognosis. The severity of proteinuria in patients with diabetic nephropathy is progressive until nephrotic syndrome.

2. Edema early diabetic nephropathy patients generally do not have edema, a small number of patients in the plasma protein decreased before, may have mild edema, when 24 hours urine protein more than 3 G, edema will appear. Obvious systemic edema, only seen in the rapid development of diabetic nephropathy.

3. Hypertension is common in patients with diabetic nephropathy. Severe nephropathy is often accompanied by hypertension, which can accelerate the progression and deterioration of diabetic nephropathy. Therefore, effective control of hypertension is very important.

matters needing attention

Here to add a point, and retinopathy, diabetic nephropathy is serious when almost 100% with retinopathy, but severe retinopathy does not necessarily have obvious renal disease. When diabetic nephropathy progresses, retinopathy often accelerates.