What symptom does anticardiolipin antibody positive have

summary

I've been married with my husband for several years. I wanted to have a baby, but I didn't get pregnant. At that time, I felt that I was young and had nothing to do with it. Now I felt a little worried, so I went to the hospital for examination. The blood test showed that I was positive for anticardiolipin antibody. The doctor said that it would lead to infertility or abortion. Now let's share with you.

What symptom does anticardiolipin antibody positive have

First, anticardiolipin antibodies are a group of antibodies that can be associated with a variety of antigen substances containing phospholipid structure. They are common in autoimmune diseases, ischemic encephalopathy, viral hepatitis, syphilis, and habitual abortion. The antibody is closely related to thrombosis, platelets, spontaneous abortion or intrauterine death.

Second, anticardiolipin antibody is a kind of autoantibody, which takes cardiolipin with negative charge on platelet and endothelial cell membrane as target antigen. This antibody acts on the membrane phospholipids of placental vascular endothelial cells, leading to thrombosis and trophoblast cell function changes, the formation of placental infarction, fetal death, and then lead to abortion. Specifically, the positive anticardiolipin antibody may lead to recurrent abortion and other adverse pregnancy outcomes.

Third: anticardiolipin antibody is a group of antibodies that can be related to a variety of antigen substances containing phospholipid structure. The positive anticardiolipin antibody APA indicates that there may be antiphospholipid syndrome, which is mainly manifested as repeated hypercoagulable state of blood, thrombosis, thrombocytopenia, often accompanied by repeated abortion and stillbirth. The pathogenesis is related to local antigen reaction caused by antiphospholipid antibody, decidual hemorrhage It is related to vascular lesions, extensive thrombosis and infarction in the placenta, leading to chronic placental insufficiency, fetal development stop or stillbirth.

matters needing attention

Positive anticardiolipin antibody may lead to adverse pregnancy outcomes such as recurrent abortion. It is suggested to go to the hospital for treatment as soon as possible. The treatment is generally oral aspirin, injection of human immunoglobulin, heparin, hormone and other methods.