What are the conditions for bone marrow transplantation

summary

Some patients with leukemia must choose bone marrow transplantation if they want to recover. But not everyone is suitable for this kind of operation. If you don't find the right bone marrow, you can't complete the operation. Let's talk about the conditions of bone marrow transplantation.

What are the conditions for bone marrow transplantation

First, we must find a suitable matching, because the probability of HLA matching is very low, even for siblings is only 1 / 4, so although the establishment of bone marrow bank is usually used in the international community to find matching donors in non blood related groups, the matching probability is between 1 / 1000 and 1 / 10000. In fact, the vast majority of patients can not find the right ligand, but the disease is delayed.

Second: the amazing cost of surgery. If the patient is lucky enough to find the right ligand, the next hurdle is at least 300000 yuan. This is an astronomical number for many patients in China. They had to give up the operation because they couldn't raise the huge sum of money. According to relevant statistics, in the central and western regions of China, the number of people who die at home due to illness is estimated to be 60% - 80% because they can't afford to see a doctor or stay in a hospital. Although some people have received social assistance through the media, they are in the minority after all.

Third, if patients are lucky enough to have the above conditions and pass the first two hurdles, they have to face three problems, namely, the impact of radiotherapy and chemotherapy, the infection of pathogenic microorganisms, and the rejection of the body. Any one of these problems can make patients face the test of life and death, only 60 ~ 70% of the patients can pass the three hurdles. Another important drawback of bone marrow transplantation is that there are very few bone marrow types suitable for transplantation, because it is very difficult to find bone marrow suppliers with the same HLA matching.

matters needing attention

Even if you have enough surgery costs, but you can't find your own bone marrow, you can't have surgery, and some patients will have immune rejection. Therefore, in order to successfully complete the operation of bone marrow transplantation, we need to pay attention to and consider many preconditions.