How to take medicine kidney damage to do?

summary

"Medicine is divided into three kinds of poisons". Drugs can not only cure diseases, but also cause diseases. The so-called "pathogenicity" refers to the adverse reactions of drugs, among which the renal function damage caused by drugs is a common adverse reaction. So here's how to take medicine for kidney damage? I hope this problem can help some people.

How to take medicine kidney damage to do?

First, the kidney is an important organ for metabolism and excretion of drugs, so it is also the main target organ of drug damage. Generally speaking, most drugs are excreted from the kidney after being metabolized by the liver. When the liver function is abnormal, the burden of drug metabolism from the kidney increases significantly. Some drugs are only metabolized and excreted in the kidney, and they accumulate and precipitate in the kidney tissue, eventually leading to renal tissue damage.

Second, there are great individual differences in drug-induced renal damage, which is related to many factors, such as the time and dose of drug use, the physiological state of patients, the existing basic diseases and so on. The most common drug-induced renal damage is in patients with previous renal disease or renal insufficiency, especially in patients with potential renal insufficiency, such as the elderly.

Third, there are many kinds of drugs that cause kidney damage, including traditional Chinese medicine, western medicine and various preparations. At present, the most common drugs causing renal damage in China include antibiotics, contrast agents, antipyretic analgesics, diuretics and dehydrators, traditional Chinese medicine and proprietary Chinese medicine. Because the chemical composition of Western medicine is clear, preclinical research is more in-depth, we can be vigilant and strengthen prevention for the possible nephrotoxicity, and the nephrotoxic effect of traditional Chinese medicine is often ignored by the public.

matters needing attention

Generally speaking, excessive dose and long course of treatment are the main causes of renal damage after medication. Therefore, the first principle is to adhere to rational drug use and avoid drug abuse. For the elderly, patients with underlying diseases and patients with renal insufficiency, we should evaluate their renal function before medication, adjust the dosage according to the level of glomerular filtration rate, and avoid the combined use of multiple nephrotoxic drugs and the abuse of antibiotics.