What is Turcot syndrome?

summary

Turcot syndrome is also known as glioma polyposis syndrome. It is characterized by familial multiple colonic adenomas with central nervous system malignancies. It is very rare in clinic. It can be affected by both men and women. The age of onset is 2-84 years old, with an average of 17 years old. What is Turcot syndrome?

What is Turcot syndrome?

The syndrome is a hereditary disease. Due to the small number of cases, the large proportion of single cases, the patients died before marriage, and they can not get valuable information from their offspring, so there are two theories about the genetic mode. 1. Recessive inheritance theory, based on the family reported by Turcot and Baughman, ITO studied six families and found that all families occurred in siblings, and none of the patients' parents found polyposis or brain tumor; The ratio of male to female was 6:8; He has a history of close marriage. 2. According to the dominant inheritance theory, this syndrome is a subtype of familial colonic adenoma as well as cardner's syndrome. It is based on the fact that the syndrome often occurs in the family of familial colonic adenoma.

The main treatment was operation. Once diagnosed, polypectomy or early colectomy should be performed immediately. Colonoscopy should be performed regularly after operation. Drugs and radiotherapy have certain effects on multiple tumors which are difficult to be resected by surgery.

Barium enema, barium meal X-ray and endoscopy have practical clinical value in the diagnosis of colonic adenoma or tumors in other parts of digestive tract. CT, Mir and cerebral angiography are helpful for early detection of nervous system tumors. Most of the symptoms before canceration are not obvious, and irregular abdominal pain, diarrhea, bloody stool or bloody mucus caused by colonic polyposis can first appear. The symptoms caused by glioblastoma can also be seen, such as abdominal pain, diplopia, visual impairment, motor disturbance and so on.

matters needing attention

Diet attention crucian can be anti-inflammatory detoxification, has a great help to their own condition, so I made a white radish crucian carp soup. The method is very simple. First, cut the white radish into pieces, and then cut the crucian carp into pieces. First, fry the carp pieces, add the seasoning, then stew with water, and then stew with radish. The prognosis is poor, most of the cases died within a few years after diagnosis. The reason is that the nervous system tumors can not be completely removed in most cases, and they have died of brain tumors before the canceration of colonic polyps.