The symptoms of reflux esophagitis are grade B

summary

Reflux esophagitis B class, this disease everyone, do not know about it? This is a kind of disease that affects human health. There are many reasons for this disease. Next we will introduce the symptoms of reflux esophagitis B? We can better understand the causes of these diseases through this knowledge. We can also better understand the harm of these diseases to us.

The symptoms of reflux esophagitis are grade B

1. Damage of anti reflux barrier the lower esophageal sphincter (LES) is a high pressure area within 3-5cm above the boundary between esophagus and stomach. The resting pressure is 15-30mmhg, which forms a pressure barrier and plays a physiological role in preventing gastric contents from flowing back into the esophagus. The increase of normal intra-abdominal pressure can cause Les systolic reflex through vagus nerve, which can double LES pressure to prevent GER. When LES pressure is too low and intra-abdominal pressure is too high, it can lead to ger. Cholinergic and β- Adrenergic agonists α- Adrenergic antagonists, dopamine, diazepam, calcium receptor antagonists, morphine, fat, alcohol, caffeine, smoking and other food factors can affect the function of LES and induce GER. In addition, during pregnancy, oral progesterone containing contraceptives and late menstrual cycle, the plasma progesterone level increased, and the incidence of GER increased accordingly.

2. Dysfunction of esophageal acid clearance function normal esophageal acid clearance function includes esophageal emptying and salivary neutralization. When acid gastric contents reflux, it only needs 1-2 times (10-15 seconds) of secondary esophageal peristalsis to empty almost all reflux. A small amount of acid remained in the esophageal mucosal lacunae can be neutralized by saliva (normal people have 1000-1500 ml saliva per hour, pH 6-8, entering the stomach through the esophagus). The function of esophageal acid clearance is to reduce the time limit of esophageal mucosa soaking in gastric acid, so it can prevent reflux esophagitis. Saliva secretion almost stopped during sleep at night, and secondary peristalsis of esophagus was also rare. The clearance of esophageal acid profile at night was obviously delayed, so the harm of GER at night was more serious.

3. The function of esophageal mucosal anti reflux barrier is damaged. When the barrier is damaged, esophagitis can be caused even under normal reflux. Studies have found that the proliferation and repair ability of esophageal epithelial cells is one of the important reasons for reflux esophagitis.

matters needing attention

So when our body appears, health problems must be found in time, and then go to the hospital for treatment in time, so that we can have a healthy body.