What are the manifestations of liver transplantation rejection

summary

An uncle in his family had liver problems because he was always drinking. Recently, he had just finished liver transplantation, but he was forced to repeat the operation due to rejection. Let's share with you the common problem of rejection after liver transplantation!

What are the manifestations of liver transplantation rejection

Symptom 1: hyperacute rejection: hyperacute rejection is a humoral immune response mediated by antibodies. It occurs within a few minutes to hours after the recovery of perfusion of the transplanted liver, resulting in diffuse small blood vessel thrombosis of the transplanted liver, resulting in graft failure. This phenomenon is rare, and the harm to the body is very small, we must pay attention to the protection of the body.

Symptom 2: acute rejection: the most common type of rejection. Most of them occurred from the first week to the third month after operation. Because of the use of anti rejection therapy, acute rejection can also occur one year or even one year after surgery. Immunosuppressants can significantly reduce the incidence and severity of acute rejection.

Symptom 3: chronic rejection: chronic rejection usually occurs one year after surgery. It can last for months or even years. The occurrence of chronic rejection is usually imperceptible, causing liver function damage slowly, and the treatment is difficult. In recent years, the application of new immunosuppressants tacrolimus and xixie has reversed some cases of chronic rejection. In addition, you can also do a good job in daily health care to minimize the incidence of rejection: such as appropriate use of immunosuppressants (excessive or insufficient amounts are easy to lead to chronic rejection), to avoid infection, and so on.

matters needing attention

Whether there are factors that reduce the concentration of immunosuppressants, such as diarrhea, vomiting, dyspepsia, drug interactions, etc. Once found, the transplant center should be informed and corrected immediately. Do not drink, do not eat some stimulating food, to maintain a good sleep, eat some fresh fruits and vegetables, as far as possible do not eat greasy food.