Persistent diarrhea in children?

summary

Infantile diarrhea, or diarrhea disease, is a group of digestive tract syndrome caused by multiple pathogens and factors, which is characterized by the increase of stool frequency and the change of stool characteristics. It is one of the most common diseases of infants in China. The incidence rate of infants aged 6 months to 2 years is high, and about half of them are under one year old. This is one of the main causes of malnutrition and growth and development disorders in children. Diarrhea caused by the same disease often has similar clinical manifestations, but each has its own characteristics. Clinically, it can be divided into: acute diarrhea with a continuous course of less than 2 weeks, persistent diarrhea with a course of 2 weeks to 2 months, and chronic diarrhea with a course of more than 2 months. Persistent diarrhea in children? Let's talk about it.

Persistent diarrhea in children?

In severe malnutrition, the gastric mucosa atrophies and the acidity of gastric juice decreases, which weakens the bactericidal barrier function of the stomach. It is conducive to the proliferation of bacteria and yeasts in the gastric juice and duodenal juice. The mucosa of duodenum and jejunum becomes thinner, the villi atrophy and degeneration, and the cell abscission increases, The activities of disaccharidase, especially lactase and brush border peptidase decreased, and the effective absorption area of small intestine decreased, resulting in the indigestion and malabsorption of various nutrients;

In diarrhea of severe malnutrition infants, the number of bacteria in the upper part of the small intestine increased significantly, and anaerobic bacteria and yeasts in the duodenum overmultiplied;

The immune function of severe malnutrition children is deficient. The effective IgM antibody against G-bacilli, secretory IEA antibody, phagocytic function and complement level are decreased, which increase the susceptibility to pathogens and food protein antigens. Therefore, when malnourished children suffer from diarrhea, it is easy to be delayed, and persistent diarrhea aggravates malnutrition. Both of them are cause and effect each other, eventually leading to low immune function, secondary infection, forming a vicious circle, leading to multiple organ dysfunction.

matters needing attention

1. Actively look for the causes of the course of disease, treat the causes, avoid the abuse of antibiotics, and avoid stubborn intestinal flora imbalance. 2. Prevent and treat dehydration, correct electrolyte and acid-base balance disorder. 3. Nutrition treatment