Rejection symptoms of liver transplantation

summary

My grandfather's health is not good, liver problems, ready to do liver transplantation, so what is the clinical risk of liver transplantation? What are the rejection symptoms of liver transplantation?

Rejection symptoms of liver transplantation

Symptoms 1. The early clinical manifestations of liver transplantation rejection include fever, fatigue, drowsiness, loss of appetite, tenderness in the liver region, and increased ascites; bile drainage can be seen as bile thinning, color lightening, and volume reduction, which need more attention in clinical practice.

The second symptom is the rejection of liver transplantation. The blood biochemistry is increased, including bilirubin, transaminase and alkaline phosphatase, eosinophils and lymphocytes in peripheral blood and liver transplantation. Serum neopterin, SIL-2 receptor, guanine dehydrogenase, amyloid a protein and a-microglobulin increased.

The third symptom is that the cost of liver transplantation will also be increased, and the transplanted liver is often enlarged and hardened, but portal hypertension is rare. The pathological manifestations of the liver were destruction of interlobular bile duct, progressive fibrosis, disappearance of cell infiltration in the portal area, fibrosis of the intima and sometimes foam cells. VBDS is almost irreversible. A liver transplant is needed.

matters needing attention

Immunosuppressive agents should be used to prevent and treat liver transplantation rejection. Its function is to inhibit cell-mediated immune response. Inhibition of cytotoxic T lymphocytes, inhibition of cytokine gene activity (IL-1, IL-2, IL-3, IL-4, TNF-a). Immunosuppressants include cyclosporin A and corticosteroids (hydrocortisone, prednisone, prednisolone, methylprednisolone). The scheme should be individualized.