What is the effect of vacuolar sella on life?

summary

Vacuolar sella is generally divided into primary and secondary diseases, but vacuolar sella will not affect life. Empty sella syndrome makes the pituitary smaller and larger, and causes some clinical symptoms, such as headache and dizziness. It can be primary or secondary pituitary tumor, which generally needs surgery. Cavitation sella generally does not affect people's lives, so you don't have to worry about it.

What is the effect of vacuolar sella on life?

Only 41.5% of the septum was intact, 21.5% of the septum was a 2 mm wide ring, and 5.1% of the septum was completely absent. In this group, the incidence rate of primary vacuoles due to sellar septal defect was 5.5%. When the sellar septum is incomplete or absent, the subarachnoid space is herniated into the sella under the continuous action of pulsatile cerebrospinal fluid pressure, resulting in the enlargement of sella turcica, bone absorption, decalcification, compression and atrophy of the pituitary gland, which becomes flat and adheres to the sella floor.

Even if the intracranial pressure is normal, the CSF pressure can also be caused by the sellar septal defect. The normal pulsatile CSF pressure can be transmitted into the sella and cause the change of sellar bone. Foley thinks that the possibility of cavitating sella turcica caused by chronic intracranial hypertension is the greatest. Arachnoid adhesion in sellar region is one of the important factors for the occurrence of this disease. It may be that the cerebrospinal fluid drainage is not smooth due to the local adhesion in sellar region, that is, under the action of normal pulsatile pressure of cerebrospinal fluid, the sellar septum is impacted, and gradually makes it sink, thin and open. After the sellar septum is opened (defect) to a certain extent, the subarachnoid space and the anterior lower part of the third ventricle can hernia into the sella.

Endocrine factors in pregnancy pituitary is physiological hypertrophy, can increase 2-3 times, multiple pregnancy pituitary continues to increase, pituitary changes in pregnancy may be the sellar septal foramen and pituitary fossa support, after delivery lactation pituitary gradually retracted, so that the sellar septal foramen and pituitary fossa left a larger space, conducive to subarachnoid hernia into the saddle. Primary vacuolar sella is more common in middle-aged women with multiple pregnancies, which may be related to this. The pituitary gland can be hyperplastic and hypertrophic in patients with hypofunction or failure of endocrine target glands (gonad, thyroid and adrenal gland). After replacement therapy with corresponding target hormone, the hyperplastic pituitary gland can be retracted, resulting in vacuolar sella turcica.

matters needing attention

Intrasellar non neoplastic cysts can be caused by calcification of the remnant part of the Leske's pouch in the middle of the pituitary gland, which increases during pregnancy and shrinks slightly after delivery. Secondary vacuolar sella turcica is caused by intrasellar or parasellar tumors after radiotherapy or surgery. According to domestic reports, the majority of primary vacuolar sella turcica is caused by sellar adhesion (about 50%), which causes sellar septal defect, sellar adhesion and pituitary atrophy.