Half year old jaundice symptom?

summary

In medicine, the jaundice of a baby under the age of 28 days is called neonatal jaundice. The main symptoms are yellowing of skin, mucous membrane and sclera, loss of appetite and restlessness of the baby, and the temperature may also rise. Neonatal jaundice is a very common disease in newborns. Clinically, about 85% of full-term infants and the vast majority of premature infants have jaundice within one week after birth. Neonatal jaundice is mainly caused by the imperfect development of liver function, abnormal bilirubin metabolism and the increase of bilirubin concentration in blood. It can be divided into physiological jaundice and pathological jaundice. Half year old jaundice symptom? Let's talk about it

Half year old jaundice symptom?

Infectious jaundice is due to viral infection or bacterial infection and other reasons, resulting in liver cell function damage and jaundice. Most of the virus infections were intrauterine, and the most common were cytomegalovirus and hepatitis B virus. Other infections were rubella virus, Epstein Barr virus and Toxoplasma gondii. The most common bacterial infection was septicemia and jaundice. Jaundice is characterized by persistent jaundice after physiological jaundice or persistent jaundice after physiological jaundice subsides.

The most common cause of hemolytic jaundice is ABO hemolysis, which is caused by the blood group incompatibility between the mother and the fetus; Others, such as maternal blood group A, fetal blood group B or AB; Maternal blood group B and fetal blood group A or AB are rare, and jaundice is mild. It is reported that the incidence rate of ABO blood group incompatibility hemolytic disease is 11. 9%。 Neonatal hemolytic jaundice is characterized by jaundice within 24 hours after birth, and gradually aggravated. Early blood exchange therapy can be carried out, if it is a slight symptom caused by ABO blood group, as long as the use of light therapy.

Jaundice caused by breast milk is called breast milk jaundice, which is a special type of pathological jaundice. A small number of breast-feeding newborns, the degree of jaundice than normal physiological jaundice, the reason is not very clear. Its jaundice characteristic is: after the physiological jaundice peak, the jaundice continues to aggravate, if continues to lactate, the jaundice continues under the high level condition for a period of time only then slowly drops, if stops lactation 48 hours, the jaundice obviously drops, if again lactation, the jaundice rises. Because pregnant diol hormone is contained in breast milk, it can inhibit the activity of glucuronidase in the liver of newborns, resulting in the bilirubin in the blood can not be metabolized and excreted in time, so the concentration of bilirubin in the blood increases, resulting in neonatal skin and sclera yellowing.

matters needing attention

A new viewpoint of drug treatment of jaundice: the use of porphyrin in tin (SNMP). It is the only heme analogue approved by FDA for clinical use. Heme oxygenase (HO) is the rate limiting enzyme for the production of bilirubin by heme metabolism. Inhibition of HO activity can reduce the production of bilirubin. Therefore, it is more reasonable to use ho when the bilirubin treatment function of neonatal liver is not mature. Tin porphyrin does not enter the brain tissue, has a wide range of safe dose, and is not degraded in vivo, The heme, which was blocked by SNMP and could not be degraded, would not accumulate in the tissue, but was discharged into the biliary system in the original form by the liver and excreted through the intestine.