Symptoms of poisoning

summary

Benzene poisoning can be divided into acute benzene poisoning and chronic benzene poisoning. Acute benzene poisoning is a pathophysiological process characterized by central nervous system anesthesia after oral administration of benzene containing organic solvents or inhalation of high concentration benzene vapor; Chronic benzene poisoning is that benzene and its metabolites phenols directly inhibit the nuclear division, leading to cell mutation, affecting the hematopoietic function of bone marrow. The clinical manifestation is the continuous decrease of white blood cell count, which eventually develops into aplastic anemia or leukemia.

Symptoms of poisoning

(1) Nervous system headache, vertigo, tinnitus, diplopia, faltering gait, drunkenness, drowsiness, convulsion, coma, respiratory paralysis, delirium, hallucination and brain edema in severe cases, and peripheral nerve damage in a few patients; Further development for consciousness fuzzy aggravation, into shallow coma state, call should not, continue to inhale high concentration of benzene into deep coma. In severe cases, respiratory arrest, cardiac arrest. The course of the disease depends on the concentration of benzene in the air. From a few minutes to a few hours, active rescue before cardiac arrest can recover in a few minutes to a few hours. If deep coma occurs, people who inhale high concentration may have "lightning like" death.

(2) Respiratory system can be seen in inhalation poisoning, cough, suffocation, chest tightness, severe lasting for a long time, or weak breathing, can be complicated with hypoxic pulmonary edema, can be accompanied by eye irritation.

(3) The circulatory system blushes, palpitations, blood pressure drop, shock, myocarditis, various arrhythmias and even ventricular fibrillation can occur. One to two degrees of atrioventricular block can be seen on ECG.

matters needing attention

According to a short-term history of inhaling a large amount of high concentration benzene vapor or mistaking benzene, central nervous system depression (drunken state) can be diagnosed. Conduct poison detection when necessary. Pay attention to identify with other organic solvents (halogenated hydrocarbons, ethers, ketones, etc.) poisoning.