How does proteinuria 1 return a responsibility

summary

I am 27 years old, male, recent physical examination urinary protein 2 +, never had before, the doctor suspected nephritis, review several times are 2 + after treatment improved, now to share the next urinary protein 1 how to return a responsibility.

How does proteinuria 1 return a responsibility

Reason 1: glomerular filtration of plasma protein, glomerular filtration membrane from inside to outside by capillary endothelial cells, glomerular basement membrane and renal vesicle visceral layer epithelial cells.

The second reason is that the capillary wall of normal glomerulus is negatively charged, so it is not easy for negatively charged proteins to leak out, which is called electrical barrier function. The function of basement membrane is very important. It has been suggested that the reduction of negative charge of glomerular wall fixation will not only lead to a large number of proteins entering the urinary cavity, but also make the larger molecular substances accumulate in the mesangium, and even affect the circulating immune complexes and make them deposit on the glomerular basement membrane.

The causes of low molecular weight of glomerular lysozyme, albumin, myoglobin, transferrin, etc. There may be less than 30 mg / min protein in urine, but it is almost completely reabsorbed by renal tubules; when the glomerular basement membrane is damaged, the basement membrane thickens, the pores increase, the protein leakage increases, or the renal tubule lesions, and the protein resorption capacity decreases, both of which can cause the increase of proteinuria.

matters needing attention

Warm reminder: if there is urine protein, it means that the renal filtration function has decreased, and further examination is needed. If the urine protein is positive for several times and more than 2 plus signs, it indicates that the patients may have glomerulonephritis, pyelonephritis, nephrotic syndrome and other related diseases. At this time, we need to seize the time of treatment, find the root cause of symptomatic treatment.