Symptoms of drug hepatitis

summary

Drug induced hepatitis can be divided into four clinical types: hepatitis type, fatty liver type, intrahepatic cholestasis type and cholestasis with inflammation type according to different pathological manifestations and lesion sites

Symptoms of drug hepatitis

Intrahepatic cholestasis: the patient presented with jaundice, but no fever or rash, and no increase of eosinophils. Liver function examination: transaminase and bilirubin were increased, cholesterol and alkaline phosphatase were normal. Pathological examination showed cholestasis in the center of hepatic lobule and bile examination in the capillary bile duct.

Hepatitis patients have fatigue, nausea, vomiting, anorexia, dark urine color, hepatomegaly, tenderness and other clinical symptoms similar to hepatitis. Liver function test: transaminase, hemin were increased, flocculent reaction was positive, prothrombin time was prolonged. Pathological examination: the liver cells were damaged and showed focal massive necrosis.

The patients with fatty liver had nausea, vomiting, anorexia, liver pain and other clinical symptoms. Liver function test: transaminase increased, serum bilirubin could exceed 17.1 μ molgl, flocculent test showed negative reaction. Pathological examination showed a large amount of fat deposition in hepatocytes, necrotizing inflammation and cholestasis.

matters needing attention

I hope it will be helpful to my friends. If the dosage is too large, taking the medicine for too long will cause damage to the human liver. We should monitor the liver function at any time. Especially for people with allergic constitution, we should pay attention to drug care. The symptoms and treatment methods of drug-induced hepatitis are introduced here. Patients must go to the hospital as soon as possible, and maintain a high degree of vigilance for patients with drug-induced hepatitis.