Why do the elderly suffer from hypocalcemia?

summary

As soon as people get old, there will be many diseases. Hypocalcemia is a common disease in the elderly. The emergence of this disease has seriously affected the health of our patients. If the treatment is not timely, our patients will have the symptoms of hand and foot twitch and osteoporosis. Here is to introduce why the elderly will suffer from hypocalcemia.

Why do the elderly suffer from hypocalcemia?

Vitamin D and calcium deficiency are the most common causes of hypocalcemia in the elderly. Other common causes of hypocalcemia are: ① hypoparathyroidism (parathyroid hypothyroidism), ② pseudohypoparathyroidism (pseudoparathyroidism), ③ chronic renal failure, ④ acute pancreatitis, ⑤ chronic diarrhea and intestinal malabsorption syndrome.

Pseudohypoparathyroidism: due to PTH dysfunction, the target organ is resistant to PTH. There are at least two types: type Ia and type IB. Type Ia is autosomal dominant inheritance, which may be related to the mutation of Gs protein gene, which limits the normal response of camp to PTH; Type Ib may be caused by PTH receptor deficiency, but it has not been confirmed.

Hypomagnesemia can not only inhibit PTH secretion, but also affect its function, so it can cause hypoparathyroidism. Magnesium replacement therapy can correct this defect, so the hypoparathyroidism is reversible.

matters needing attention

The most common causes of hypocalcemia in the elderly are vitamin D and calcium deficiency, because the elderly are more likely to lose calcium than other age groups, and the intake of calcium in daily life is insufficient, which leads to hypocalcemia. Other diseases may also lead to inadequate absorption of calcium and low serum calcium content.