Does metformin enteric coated tablet hurt stomach?

summary

Is metformin harmful to the stomach? Metformin is the first choice for type 2 diabetes mellitus, especially obese type 2 diabetes mellitus, which is ineffective in diet control and physical exercise. So does metformin harm the stomach? Take a look.

Does metformin enteric coated tablet hurt stomach?

In the early stage of metformin administration, especially on an empty stomach, about 10% ~ 20% of patients will have gastrointestinal discomfort, including nausea, vomiting, loss of appetite, metal odor in the mouth, thin stool and diarrhea. This is because of the stimulation caused by the high concentration of metformin hydrochloride adhering to the gastrointestinal mucosa after the ordinary form of metformin dissolves in the stomach immediately. These adverse reactions are generally one-time (lasting for about 3-10 days), which can be tolerated by most people, and can be alleviated by continuous medication.

Patients with allergy to this product, diabetic ketoacidosis, liver and renal insufficiency (serum creatinine more than 1.5mg / dl), pulmonary insufficiency, heart failure, acute myocardial infarction, severe infection and trauma, major surgery and clinical hypotension and hypoxia, alcoholism, vitamin B12, folic acid deficiency, severe diabetic nephropathy, diabetic fundus lesions It is forbidden for pregnant and lactating women.

Patients with a history of lactic acidosis and elderly patients should be cautious. As this product may accumulate lactic acidosis, once it occurs, it will lead to life-threatening. Therefore, renal function should be monitored and the minimum effective dose should be given to reduce the risk of lactic acidosis. In case of fever, coma, infection and other stress states, the use of this product should be temporarily stopped during surgery and examination with iodine containing contrast agent, as it may lead to the deterioration of acute renal function. This product can cause hypoglycemia when combined with sulfonylureas and insulin. Avoid drinking alcohol when taking this product. It is easy to cause hypoglycemia or lactic acidosis. It should be used with caution in patients with poor liver function. This product can interfere with the absorption of vitamin B12. It is recommended to monitor the hemogram.

matters needing attention

Active dietotherapy and massage health care: mutton, dog meat and other warm food have the effect of nourishing stomach, suitable for stomach cold disease; Garlic disinfection can help eliminate inflammation, it is recommended to eat more; In addition, medlar, tremella, jujube, walnut can be snacks or into the dishes. After dinner, before going to bed, you can rub your hands with your navel as the center and rub them clockwise for 64 circles. After that, rub your hands with your hands and massage your lower abdomen. The occurrence and development of stomach disease is closely related to people's mood and mentality. Therefore, we should pay attention to mental health, maintain mental happiness and emotional stability, and avoid the stimulation of bad emotions such as tension, anxiety and anger.