How many years of Parkinson's disease

summary

The prevalence of PD is about 1.7% in people over 65 years old in China. Most patients with Parkinson's disease are sporadic cases, and less than 10% of them have family history. How many years of Parkinson's disease? Let me talk to you today.

How many years of Parkinson's disease

First, environmental risk factors are also the cause of Parkinson's disease. Clinical and experimental studies have proved that 1-methyl-4-phenyl-1,2,2-tetrahydropyridine poisoning is related to Parkinson's disease. At present, NPTP has been used to make Parkinson's model for experimental study.

Second, free radical damage and loss of oxidative phosphorylation are also one of the causes of Parkinson's disease. At present, experiments have proved that the free radicals in Parkinson's patients group are significantly higher than those in the control group, and the oxidative phosphorylation of mitochondrial complex 1 is defective, which are related to the damage of mitochondrial DNA and other macromolecules.

Third, because Parkinson's patients did not receive treatment on time and reasonably according to the doctor's advice, they increased or decreased the dosage at will, and even stopped the treatment when they had time. Parkinson's disease is delayed and the best time for treatment is lost due to the failure of diagnosis and treatment in time.

matters needing attention

Although understanding the etiology of Parkinson's disease can be effectively prevented, some people will unfortunately suffer from the disease, so we should also pay attention to the treatment of Parkinson's disease. In life, prevention of Parkinson from the source of disease can effectively reduce the incidence rate of Parkinson and make everyone healthy.