Antibody of rabies vaccine

summary

Human diploid cell rabies vaccine is lyophilized powder injection. China began to develop human diploid cell rabies vaccine in 2004. In 2014, China's first lyophilized human rabies vaccine with independent intellectual property rights was launched. The purified Vero cell rabies vaccine for human use and the purified hamster kidney cell rabies vaccine are both slightly cloudy white liquid. At present, the dsRNA with a length of more than 30 can cause interferon toxicity, which is a worldwide risk. Long time exposure can form dispersible precipitates and sulfur-containing thiomersal preservatives. The vaccine has a good effect on preventing wound infection. Let's talk about the antibody of rabies vaccine

Antibody of rabies vaccine

1. It is very important to clean and disinfect the wound in time (preferably within a few minutes after the bite) to prevent rabies. First use 3% - 5% soapy water or 0.1% Bromogeramine, and then wash with clean water; For deep wounds, the syringe is used to extend into the deep part of the wound for perfusion and cleaning, so as to achieve comprehensive and thorough. Then disinfect with 75% alcohol, and rub with iodine tincture. The earlier the local wound is treated, the better. Even if it is delayed for 1-2 days or even 3-4 days, the local treatment should not be ignored. At this time, if the wound has scab, the scab should be removed and treated according to the above method.

2. The wound should not be bandaged or sutured, and the open wound should be exposed as much as possible. If the wound must be bandaged and sutured (such as invading large blood vessels), it should be ensured that the wound has been thoroughly cleaned and disinfected, and anti rabies serum has been used according to the above method.

3. The level of neutralizing antibody and protection rate were the main indexes of the preventive effect of the vaccine. The neutralizing antibody appeared 7-10 days after the first immunization, and reached the protection level after 5 doses of immunization (the requirement is ≥ 0.5 IU / ml). The antibody was maintained for at least half a year. Those who bite again after half a year should be vaccinated again.

matters needing attention

(1) If the product is found to have clots or discoloration, or ampoules have cracks, liquid vaccine has been frozen, etc., should not be used（ 2) The vaccine should be used within the validity period（ 3) During the period of vaccination, you can work as usual, but do not eat wine, strong tea and other irritating food and work hard to avoid reaction（ 4) Severe bite must be combined with anti rabies serum（ 5) Spare 1:1000 adrenaline.