Causes of polycystic kidney disease

summary

Earlier, because of painful urination, suspected of stones, the kidney made a B-ultrasound, accidentally found a third of the left kidney cyst, the doctor diagnosed as polycystic kidney. But in the past 40 years, I don't think there is any problem with my kidney. What is the cause of polycystic kidney?

Causes of polycystic kidney disease

First: toxins. It is also a common cause of polycystic kidney disease. Toxins act on the human body, can cause damage to various cells, tissues and organs, resulting in diseases and even life-threatening, and it is also one of the main reasons for gene mutation, congenital dysplasia and other phenomena. Common toxins such as pesticides, certain chemicals, radiation, pollution, etc. In particular, it should be pointed out that some drugs also have nephrotoxicity, if used improperly, it is easy to cause renal damage.

Second: gene mutation is not hereditary: for polycystic kidney disease, it is mostly inherited through parents' genes, which are divided into autosomal dominant inheritance and autosomal recessive inheritance. However, some patients with polycystic kidney disease are neither inherited by parents nor belong to congenital dysplastic polycystic kidney disease, but gene mutation during embryo formation. In the process of embryo formation, due to the role of various factors, gene mutation, the formation of polycystic kidney disease, although this situation is rare, but it can still occur, therefore, some patients with polycystic kidney disease may not have a parental genetic history. This is a common cause of polycystic kidney disease.

Third: all kinds of infection: infection can cause abnormal changes in the internal environment of the organism, thus creating environmental conditions conducive to gene changes of cysts, enhancing the activity of internal factors of cysts, thus promoting the formation and growth of cysts; Common infections include upper respiratory tract infection, including cold, urinary tract infection, gastrointestinal tract infection, skin infection, trauma infection, instrument infection and so on, that is, bacterial infection or viral infection can have a great impact on the cyst.

matters needing attention

Congenital dysplasia can produce a variety of diseases. For cystic nephropathy, it can mainly cause medullary sponge kidney, dysplastic polycystic kidney disease, etc. the gene of congenital dysplasia is not abnormal, so it is different from gene inheritance or gene mutation. This is a common cause of polycystic kidney disease.