How to treat gallstones? Litholytic therapy

summary

The main symptoms of gallstones are fever and chills, jaundice, abdominal pain and a series of other symptoms, which seriously endanger the health of patients

How to treat gallstones? Litholytic therapy

First: litholytic therapy (oral cholic acid and other drugs): at present, the main drugs for litholytic therapy are chenodeoxycholic acid and its derivative ursodeoxycholic acid. Indications for treatment: ① the diameter of gallstones is less than 2cm; ② the gallstones are X-ray transparent stones with less calcium; ③ the cystic duct is unobstructed, that is, the functional gallbladder can be shown on the oral cholecystography; ④ the liver function of the patient is normal; ⑤ there is no obvious history of chronic diarrhea. The treatment dose was 15 mg / g per day for 6-24 months. The effective rate of dissolving stone is generally 30-70%. During the treatment, B-ultrasound or oral cholecystography was performed every six months to understand the dissolution of stones. Because this kind of stone dissolving therapy is expensive, and has certain side effects and toxic reactions, it must be taken for a lifetime. For example, three months after stopping the therapy, cholesterol in bile will become supersaturated again, and the stone will relapse. According to statistics, the recurrence rate can reach 25% in three years. At present, this kind of stone dissolving therapy has certain limitations.

Second: extracorporeal shock wave lithotripsy (ESWL): the main indications of ESWL for the treatment of gallstones are cholesterol stones in the gallbladder. Oral cholecystography shows that there are no more than three stones with a diameter of 12-15mm, and only one stone with a diameter of 15-20mm. A normal gallbladder contraction function is required. Ursodeoxycholic acid (UDCA) 8 mg / kg / D was administered before and after shock wave to improve the disappearance rate of crushed stones. In order to consolidate the curative effect after the stone disappeared, it can be taken for half a year. This method is safe and effective. There is still about 11.2% stone recurrence rate. The treatment is expensive and the scope of treatment is strict.

Third: the surgical treatment of gallstones: traditional open cholecystectomy; open exploration of bile duct; laparoscopic mini incision cholecystectomy; laparoscopy combined with choledochoscope exploration of bile duct

matters needing attention

Read the above introduction, you have an understanding of the treatment of gallstone patients! Hope to help you, experts say, more exercise, develop the habit of eating breakfast, regular examination can help prevent gallstone patients treatment!