Is ketonuria the same as phenylketonuria

summary

The names of many diseases in our life look very similar, just a few words short, but the nature is very different. Let's talk about whether ketonuria and phenylketonuria are the same problems.

Is ketonuria the same as phenylketonuria

Firstly, the enzyme defect in phenylalanine metabolic pathway makes phenylalanine unable to transform into tyrosine, resulting in phenylalanine and its ketoacid accumulation and excretion from urine; ketonuria is the occurrence of a large number of ketones in urine, which are mainly produced by fat metabolism.

Then, one is the metabolic disorder of phenylalanine, and the other is caused by the massive decomposition of fat. The former is mostly congenital genetic diseases, and the latter is that people with diabetes are more likely to suffer from it. We must pay attention to diet, and do not eat very sweet food.

Finally, ketonuria is characterized by hyperglycemia, accelerated oxidation of fatty acids, and depletion of oxaloacetic acid, which is necessary for acetyl CoA to enter the citric acid cycle. Eventually, a lot of ketones appear in the blood and urine.

matters needing attention

In life, we should develop good living habits, do not eat stimulating food, do not eat very sweet food, eat more fresh fruits and vegetables, can use natural sources of high-quality protein, such as: lean meat, eggs, fish.