Symptoms of HIV pulmonary tuberculosis?

summary

Due to the attack of HIV, the immune function of HIV / AIDS patients is destroyed, and often accompanied by a variety of opportunistic infections. In these opportunistic infections, tuberculosis is one of the most common opportunistic infections of AIDS. Tuberculosis and AIDS are mutually promoting disease progression, deterioration, and infection A concomitant disease that rapidly leads to death. Symptoms of HIV pulmonary tuberculosis? I'd like to share my views with you.

Symptoms of HIV pulmonary tuberculosis?

(1) acute incidence rate is high, the condition develops rapidly. Acute cases are mainly miliary and exudative lesions. After AIDS patients are infected with Mycobacterium tuberculosis, it is easy for Mycobacterium tuberculosis to spread rapidly in the body of patients, and it is very easy to activate the inactive lesions in the body, so as to destroy the pulmonary vein and lymph, and spread to the whole body（ 2) The complications of opportunistic infection increased. Patients are prone to chronic infectious diarrhea, oral and esophageal fungal infection, pulmonary infection, gastric bleeding, anal condyloma acuminatum and other infectious diseases.

(3) The positive rate of sputum culture was lower than that of tuberculin. In the early stage of tuberculosis infection, the positive rate of acid fast bacilli in sputum was higher, and the positive rate of sputum smear was 31% - 89%; When the number of CD4 + cells was more than 200 / mm, PPD test was positive. Most of the patients had entered the middle and late stage, sputum smear was negative, the number of CD4 + cells decreased rapidly, and PPD test was negative.

(4) Long course of disease, poor prognosis and high mortality. Compared with simple tuberculosis, in AIDS patients with pulmonary tuberculosis, the incidence of drug-resistant tuberculosis strains is very high, and anti tuberculosis treatment and anti HIV treatment will have a certain restrictive effect and affect the treatment effect, and even between the two will promote the rapid deterioration of the two diseases, so the course of disease is long, the prognosis is poor, and the mortality is high（ 5) there are many blood borne diseases, especially hepatitis B and hepatitis C, especially incidence rate of male injecting drug users.

matters needing attention

When formulating treatment strategies for HIV / AIDS patients with mixed infection of tuberculosis, effective treatment and control of tuberculosis is still at the center and priority, because tuberculosis is an important cause of death of HIV infected people. Due to the serious interaction between some antiretroviral drugs and anti tuberculosis drugs, the toxicity of anti tuberculosis drugs can be increased, or the metabolic level of antiretroviral drugs can be reduced, which makes the treatment of mixed infection complicated. In principle, once tuberculosis is diagnosed, anti TB dot therapy should be carried out, and antiretroviral therapy should be postponed until the completion of anti TB therapy.