What disease is diabetes insipidus disease excuse me?

summary

Diabetes insipidus occurs when the urine volume exceeds 3L / d. The common disease causing diabetes insipidus is called diabetes insipidus. Diabetes insipidus can occur at any age, but most of them are young adults. The incidence rate of men and women is similar. Most of the onset of slow, often progressive, within a few days the disease can gradually obvious. A few of them can be sudden, and the onset date is exact. What disease is diabetes insipidus disease excuse me? Let's talk about it

What disease is diabetes insipidus disease excuse me?

Polyuria is the most significant symptom of Di patients, and CDI patients are usually in a hurry with a definite date. The urine volume was more than 2500ml / D or 50ml / (kg. D)], accompanied by thirst and polydipsia. Nocturia increased significantly, the urine volume is generally more than 4L / D, a few can be more than 10L / D, but there are also reports up to 40L / d.

The specific gravity of urine was 1.0001-1.0005, and the osmotic pressure of urine was 50-200mosm / L, which was significantly lower than that of plasma. Long term polyuria can lead to the increase of bladder capacity, so the frequency of micturition is reduced. Some patients with diabetes insipidus have mild symptoms, and the urine volume is 2.4-5 L / d. if severe dehydration is caused by limiting water intake, the specific gravity of urine can reach 1.010-1.016, and the osmotic pressure of urine can exceed that of plasma by 290-600 mOsm / L.

If the patient's thirst center is not affected and the drinking water is not limited, it will only affect sleep, weak physical strength and not easy to endanger life. If the patient's thirst decreases or disappears, and fails to replenish water in time, it can cause severe water loss, significant increase of plasma osmotic pressure and serum sodium level, extreme weakness, fever, mental symptoms, and even death. Once diabetes insipidus combined with adenohypophysis, diabetes insipidus can be alleviated, and the symptoms can reappear or worsen after glucocorticoid replacement therapy.

matters needing attention

Avoid long-term mental stimulation, long-term mental stimulation (such as threat, sadness, anxiety or tension) can cause cerebral cortex dysfunction, and then cause endocrine disorders, make antidiuretic hormone secretion more sufficient, urine volume more, make the disease more serious.