Symptoms of ethylene glycol poisoning?

summary

Ethylene glycol is also known as "glycol", "1,2-ethyleneglycol", referred to as eg. The chemical formula is (CH2OH) 2, which is the simplest diol. Ethylene glycol is a colorless, odorless and sweet liquid, which is toxic to animals. The lethal dose to human is about 1.6 g / kg. Ethylene glycol is miscible with water and acetone, but it is less soluble in ethers. It is used as solvent, antifreeze and raw material of polyester. Polyethylene glycol (PEG), a high polymer of ethylene glycol, is a phase transfer catalyst, which is also used for cell fusion; Its nitrate is an explosive. Symptoms of ethylene glycol poisoning? Let's talk about it

Symptoms of ethylene glycol poisoning?

Acute poisoning, initially manifested as inhibition of the central nervous system, similar to alcoholism, such as dizziness, dizziness, gait instability and disturbance of consciousness. Then respiratory tract irritation symptoms, cough, shortness of breath, dyspnea and other bronchitis and pulmonary edema.

It is similar to alcoholism, but there is no alcohol smell in the exhaled breath. More than a few minutes to a few hours after mistaking, mild cases appeared drunk, severe cases showed paroxysmal confusion, drowsiness, coma, convulsion, incontinence and brain edema. Convulsions were tonic clonic seizures, patients may have nystagmus, optic disc edema. The patient enters coma state, can have hypotension, tachycardia, shortness of breath, cyanosis.

Severe patients may have pulmonary edema, cardiac enlargement, congestive heart failure. Some patients have acute abdomen, and may have varying degrees of renal function damage. In severe cases, they may die due to acute tubular necrosis and urinary incontinence.

matters needing attention

Timely and repeated hemoperfusion and dialysis, elimination of toxic substances in blood and protection of kidney are the key to treatment. Gastric lavage and enema should be done as soon as possible to prevent further absorption of ethylene glycol; Correct acidosis in time; Timely rehydration and diuresis can promote the excretion of ethylene glycol from urine; Dehydration in time can prevent brain edema and protect brain cells; A large amount of ethanol should be used in time to prevent ethylene glycol from metabolizing into more toxic metabolites（ 4) Alcohol as an antidote has a certain effect, the dosage can be greater than 0.7g/l blood, early use may be better.