What effect does progesterone have

summary

Progesterone is a kind of natural progesterone secreted by corpus luteum. It has a significant morphological effect on endometrium stimulated by estrogen in vivo and is necessary for maintaining pregnancy. Compound progesterone injection is a light yellow clear oily liquid, 1ml each, containing 20mg progesterone and 20mg estradiol benzoate. It's the same as progesterone. But the effect will be better. Intramuscular injection 1ml daily for 2-4 days. Triad hormone injection is a light yellow clear oily liquid, 1ml each, containing 12.5mg progesterone, 25mg testosterone propionate and 1.5mg estradiol benzoate. It is used as compound progesterone injection.

What effect does progesterone have

First, in the late period of menstrual cycle, the glands in the uterine mucosa grow, the uterus is congested, and the endometrium thickens, so as to prepare for the implantation of fertilized eggs. After the implantation of the fertilized egg, it can produce placenta, reduce the excitability of the pregnant uterus, inhibit its activity, and make the fetus grow safely. Under the joint action of estrogen, it can promote the full development of the breast and prepare for the milk production.

Second: it is mainly used for habitual abortion, dysmenorrhea, menorrhagia or HAEMORRHEA, amenorrhea and other symptoms. Oral administration of large doses of progesterone is also used for diseases caused by progesterone deficiency, such as premenstrual syndrome, menstrual disorder caused by ovulation cessation, benign breast disease, premenopausal and menopausal period, etc. Guided administration can replace oral administration, especially for patients with liver disease. Can also be used for benign prostatic hyperplasia, sleep apnea syndrome.

Third: make the cervix closed, reduce mucus thickening, so that sperm is not easy to penetrate. The negative feedback effect on hypothalamus of large dose of the drug can inhibit the secretion of pituitary gonadotropin and produce the effect of inhibiting ovulation. The blood concentration of this product reaches the peak after 1-3 hours of oral administration. It is inactivated due to rapid metabolism, so it is generally given by injection.

matters needing attention

People allergic to progesterone should be prohibited. Patients with unexplained vaginal bleeding, thrombophlebitis, vasopressin, stroke or previous history should be cautious. Patients with kidney disease, heart disease, edema and hypertension should be cautious. Once the clinical manifestations of thrombotic diseases appear, the drug should be stopped immediately, and the drug should be stopped in time if there are symptoms of discomfort, and the doctor should consult in time.