What is nothing β Lipoproteinemia?

summary

nothing β- Lipoproteinemia; A rare congenital defect transmitted in a recessive manner to a complete absence β- Lipoprotein, dysentery, spinous red blood cells (red blood cell membrane has a sharp protrusion), retinitis pigmentosa, dyskinesia and intellectual disorders. What is non pigmentation β Lipoproteinemia? Next, I'd like to share my views with you.

What is nothing β Lipoproteinemia?

nothing β- Lipoproteinemia was caused by microsomal triglyceride transfer protein gene mutation. The absorption function of fat was significantly weakened, and there was neither chylous particles nor very low density (P < 0.05)- β) The formation of lipoprotein (VLDL), all plasma lipids were significantly reduced, no postprandial lipidemia. Without special treatment, a large amount of parenteral or oral vitamin E, a can delay or block the onset of nervous system

nothing β There was no significant difference between the two groups β The main feature of lipoprotein is malabsorption of fat; Retinopathy, visual field narrowing, macular degeneration, cataract; Ataxia, muscle atrophy; Arcuate foot; Atrophy of sexual space; Low density lipoprotein is absent.

low β The expression of HBL is similar to that of ABL. It is caused by apoB gene mutation. Heterozygous mutation of apoB gene leads to low serum apoB, VLDL and LDL cholesterol levels. Heterozygous mutation of MTP does not lead to the decrease of these components. Only homozygous MTP mutation leads to the significant decrease of lipoprotein components.

matters needing attention

Reducing fat diet as much as possible, using medium chain triglycerides and large amount of vitamin E supplementation may be effective. For most patients, diet therapy or at the same time with the correction of coexisting metabolic disorders can often reduce the blood lipid level to normal. The so-called coexisting metabolic disorder refers to hypothyroidism, obesity, uncontrolled diabetes and excessive drinking.